Gonadotropin (Pregnyl, Novarel)

HCG dosage calculator

Reconstitute HCG (human chorionic gonadotropin) and convert your dose in international units into the exact units to draw. Enter your vial strength in IU and bacteriostatic water volume for the precise mark on a U-100 insulin syringe.

Your reconstitution
Vial sizeIU
Bacteriostatic water addedmL
Desired doseIU per injection
500 IU
100 IU steps · capped at your vial size

Draw to

15units on a U-100 insulin syringe

Draw to the 15 unit mark. That is 0.150 mL of solution.

Concentration3333.33IU per mL
Volume to draw0.150mL
Doses per vial20injections

Informational and educational only. Not medical advice. This tool performs math on values you enter and is not a substitute for your prescriber.

Common questions

How many units is 500 IU of HCG?

It depends on your reconstitution concentration. With a 5000 IU vial in 2 mL of bacteriostatic water (2500 IU/mL), 500 IU is 0.20 mL, which equals 20 units on a U-100 insulin syringe. With the same vial in 1 mL (5000 IU/mL), 500 IU is 0.10 mL, or 10 units. Enter your own vial strength and water volume above to get your exact number.

Is HCG FDA-approved?

Yes, for specific indications. The chorionic gonadotropin product Novarel is FDA-approved for prepubertal cryptorchidism not due to anatomic obstruction, selected cases of hypogonadotropic hypogonadism in males, and induction of ovulation and pregnancy in appropriately pretreated anovulatory infertile women, per its prescribing information. The same label notes that HCG has no known effect on fat mobilization and is not effective for weight loss. HCG is a prescription drug; this tool does not recommend any dose or use.

How do I reconstitute HCG?

Add your chosen volume of bacteriostatic water to the lyophilized vial, directing the stream gently against the glass wall, and swirl slowly (do not shake) until fully dissolved. The calculator above converts your vial strength in IU and water volume into the exact concentration in IU/mL, the draw volume, and the units to pull for your target dose. Refrigerate and follow the storage time on your product labeling after reconstitution.

What dose of HCG should I take?

This calculator does not recommend a dose. It performs math on the values you enter so you can convert a dose your prescriber has given you into the exact units to draw. HCG doses in the FDA label vary by indication and patient, and HCG is a prescription medication. Consult a licensed clinician for any dosing decision.

Source: Novarel (chorionic gonadotropin) Prescribing Information - DailyMed (Ferring Pharmaceuticals) · How we calculate